From Families Against Mandatory Minimums:

On Wednesday, October 5, FAMM members will join other national organizations and thousands of people across the country in a National Call-In Day. People across the country will call Senate leadership – Senators Harry Reid (D-Nev.) and Mitch McConnell (R-KY) – and ask them to make the criminal justice system more fair, support public safety and reduce costs to taxpayers by passing S. 306, the National Criminal Justice Commission Act.

S. 306 would create a bipartisan commission to review current criminal justice policies and make recommendations for system-wide reform. We believe that any review of the criminal justice system will necessarily include a review (and rejection) of mandatory minimums.

Talking points and contact info available here.